Regional Hyperthermia and Immune Therapy:
Why is Hyperthermia often used in combination with immune therapies?
Hyperthermia enhances immune responses and potentiates cancer treatment.
Our Japan-based immune-therapist and his team are experienced and well published on the positive effects of hyperthermia on anti-cancer immune responses that can be achieved especially when the host immune system is functioning adequately.
For this reason many patients; both early in diagnosis or, even patients with advanced cancer; choose to have cell–based immune therapies BEFORE they begin a chemotherapy or chemo radio-therapy program.
In cancer patients, the number & activity of immune cells are often decreased due to immuno-suppression by the cancer itself as well as by (often) necessary therapeutic treatments such as chemotherapy & radiation.
Under such circumstances, hyperthermia should be combined with immune-potentiation in order to increase activity of anti-cancer cytotoxic immune cells & exert value-add synergistic effects.
Hyperthermia treatments can also be used in combination with other cancer treatments.
How Hyperthermia helps the immune activation process:
NK cells harvested from the patient by apheresis & safely expanded in the laboratory, possess high numbers of activating NK receptors. These receive strong activation signals from NK activation ligands expressed in abundance on fever-range hyperthermia–treated cancer cells – leading to aggressive attacks on cancer cells.
Hyperthermia also induces heat shock proteins (HSPs)** in cancer cells & enhances antigen-specific cytotoxic T lymphocyte (CTL) induction via efficient cross-presentation by dendritic cells (DCs)
** Heat shock Protein – a protein induced in a living cell in response to a rise in temperature above the normal level.
Hyperthermia as a value add healing modality has a long in history in Europe, especially Germany. Research on hyperthermia in Japan was started by the Hyperthermia Study Group in 1978; then the Japanese Society of Hyperthermic Oncology (JSHO) was established.
Supported by the Japanese Government and intensively researched; access to hyperthermia for clinical use in patients in Japan has been available for some time. Hyperthermia can be targeted or delivered locally by means of heated pads or delivered to a patient’s whole body. Whole body hyperthermia is a very intensive procedure and must be delivered with skill and experience.
Our colleagues also utilise other heat producing non-radiation methods of hyperthermia including microwave heating equipment & radiofrequency (RF) capacitive heating equipment.
Role of the Cancer Navigator:
The Cancer Navigator fills many job descriptions while helping patients access overseas cancer treatments such as – immune therapies, hyperthermia, proton beam therapy and other advanced cancer technologies.
Immunotherapy & Hyperthermia together are also suitable for Cancer Survivors:
Conventional cancer treatments can sometime leave survivors with long term health issues. These may included compromised immunity – especially the part of the immune system that creates & hosts our cancer fighting cells e.g. NK cells, T-cells & dendritic cells.
Therefore – personalised immune therapies that can boost your own immune system by using your own white cells make a lot of sense. Of course, we have scoured the world for the best immune therapy doctors with longevity in the field. Not all cell vaccines are the same and not all doctors are experienced and qualified – so I advise caution.
Once again – we strongly advise that that you DO NOT try to do your own research and self-refer.
The benefits of adding cancer vaccines & hyperthermia to your other treatment protocols.
*You can value add 25%- 35% effectiveness to other treatments by using immunotherapy. From 2004 until now (2018) our colleagues cite more than 5000 patients who have been administered with their own NK cells, CTLs, DCs etc.